Known as the “Mother City”, Santa Fe de Antioquia is adorned with beautiful colonial architecture, cobblestone streets, colorful wooden windows everywhere you look and the majestic Puente de Occidente.
Santa Fe de Antioquia is on the list of Network of Colombian Heritage Villages, a place full of history and culture; it is considered “the cradle of the paisa culture and the mother of the Antioquia department”.
In this guide you will have the necessary information to visit this adorable small town.
Discovering Santa Fe de Antioquia
Founded with the name of “Antioquia” on December 4, 1541 by Marshal Jorge Robledo in the same place where a mining town that was called Santa Fe was originally located; only until 1584 it began to be called Santa Fe de Antioquia, due to the merger of the city of Antioquia and the town of Santa Fe.
Bear in mind, the average temperature in Santa Fe de Antioquia is 23 ºC (73ºF) and the dry season is between December and March.
How to get to Santa Fe de Antioquia
The town is located in the western sub-region of Antioquia, bordered on the north by the municipalities of Giraldo and Buriticá, on the northeast by the municipalities of Buriticá, Liborina and Olaya, on the east by the municipalities of Olaya and Sopetrán, on the south by the municipalities of Ebéjico, Anzá and Caicedo, and on the west by the municipalities of Caicedo, Abriaquí and Giraldo. In addition it is located approximately 58 kilometers (36 mi) north of Medellín.
Take a 1,5-hours flight from El Dorado (BOG) in Bogotá to José María Córdova International Airport (MDE) at Rio Negro city. Once in Rio Negro you take an approximately 3,5-hours ride (56 Km) to Santa Fe de Antioquia.
Where to stay in Santa Fe de Antioquia
There you will find numerous accommodation offerings for all budgets and personal tastes; our recommendations for you are:
- Mariscal Robledo Hotel, a colonial-style hotel in the historical center.
- Casa Bixa Hotel Boutique, which includes a restaurant, outdoor swimming pool, a bar and garden and a sun terrace.
- Hotel Santa Barbara Colonial, a lovely colonial mansion.
Santa Fe de Antioquia Attractions and Activities

1. Walk through the historic center
We recommend that you start the tour in the central square, having as a starting point the Cathedral of the Immaculate Conception, which is a construction of the nineteenth century and you will fall in love with its unparalleled beauty.
As you walk through the streets you can appreciate different restaurants where to taste the traditional local dishes and delicious desserts. In addition you will find small fruit and handicraft markets.
2. Visit the municipal house of Juan Antonio Mon y Velarde
It is currently the town hall which has an imposing architecture. There you will be able to enjoy its garden and appreciate its beauty walking or taking a seat in the central part of the house.
3. Photographic session of the house of the Gómez Martínez family
It is one of the most recognized houses of Santa Fe de Antioquia and you will be able to recognize it by its majestic walls made of stone, brick and real mixture.
Being one of the largest houses, it is also the most used as a photographic scenery for tourists, so do not miss the opportunity to take a beautiful picture in its imposing wooden windows.
4. Visit the churches of Santa fe de Antioquia

Sara Colmenares holds a Doctor of Science (D.Sc.) in Ecology from the Federal University of Rio de Janeiro and a Master’s degree in Botany from the same institution. Her doctoral research focused on palm ecology in the Atlantic Forest, supported by the Rufford Foundation conservation grant.
A published researcher in the Brazilian Journal of Plant Physiology and a member of the Association for Tropical Biology and Conservation (ATBC), Sara has presented her work at international conferences across Latin America and beyond. She was awarded the COLCIENCIAS “Virginia Gutiérrez de Pineda” fellowship, one of Colombia’s most competitive academic distinctions for young researchers.
Sara founded the Sula nature tourism brand in 2018, applying her scientific expertise to develop birding and wildlife experiences across Colombia’s six natural regions. Her fieldwork took her from the cloud forests of the Andes to the Amazon basin, the Pacific coast, and the plains of the Orinoquía. She combined deep ecological knowledge with firsthand experience to create content that is both scientifically accurate and practically useful for nature travelers.
She holds a B.Sc. in Biology from the National University of Colombia, where she also taught plant ecophysiology. She speaks Spanish, Portuguese, and English.